Chuangyuan Biotechnology's proprietary strains have been granted a national invention patent for research related to alcoholic liver injury.

Recently, the invention patent certificate for "An Application of Weizmannia coagulans IOB502 Segmented Fermentation Agent in Alcoholic Liver Injury" (Patent No.: ZL 202311841530.4) independently developed and applied by Tianjin Chuangyuan Biotechnology Co., Ltd. was issued by the National Intellectual Property Administration.

This invention provides an application of Weizmannia coagulans IOB502 segmented fermentation agent in alcoholic liver injury, obtained through a two-stage fermentation method.Weizmannia coagulansThe IOB502 strain powder and formulation have high microbial activity and characteristics such as acid and bile salt resistance; at the same time, the Weizmannia coagulans IOB502 strain powder and formulation have high safety.Weizmannia coagulansThe fermented Weizmannia coagulans IOB502 formulation contains rich flavonoid aglycones and isoflavonoid aglycones, which can enhance liver ADH activity, thereby accelerating ethanol metabolism, reducing ethanol concentration in the blood, and providing a good effect in relieving intoxication; in addition, it can also improve liver SOD activity, reduce ethanol damage to the liver, thus achieving liver protection.Weizmannia coagulans）IOB502制剂含有丰富的黄酮苷元及异黄酮苷元组分，可增强肝脏ADH活力从而加快乙醇代谢，降低血液中乙醇浓度，起到较好的解酒作用；此外，还能够提高肝脏SOD活力，减轻乙醇对肝脏的损害，从而达到护肝的效果。

The Women's Federation of Binhai New Area visited Chuangyuan Biotechnology for a discussion and exchange.

News | The Beijing-Tianjin-Hebei High-tech Enterprise High-quality Development Forum grandly opened, and Chuangyuan Bio won three awards for the 2023 "High-tech Enterprise Light".

The Women's Federation of Binhai New Area visited Chuangyuan Biotechnology for a discussion and exchange.

News | The Beijing-Tianjin-Hebei High-tech Enterprise High-quality Development Forum grandly opened, and Chuangyuan Bio won three awards for the 2023 "High-tech Enterprise Light".

2024-12-23

In December 2024, Tianjin Chuangyuan Biotechnology Co., Ltd. and Haihe Dairy jointly held a series of themed activities titled "Party Building Mutual Visits and Learning" to further promote the deep integration of both parties' party building work and business development. During the event, both sides will conduct company visits and on-site discussions. Recently, Haihe Dairy made an initial visit and, after gaining a deep understanding of Chuangyuan Biotech's products, expressed high recognition and close attention, laying a solid foundation for future cooperation. Subsequently, both parties engaged in detailed communication on the core topics of "exchange of party building experiences and sharing of business resources," discussing standardized construction of party branches, distinctive party building measures, and the promotion of party-business integration. They also conducted in-depth exchanges on aspects such as corporate cooperation, product intercommunication, and information sharing, jointly exploring new paths for the development of the health industry under the guidance of party building, providing more possibilities for further establishing a "symbiotic, mutually promoting, and win-win" cooperative relationship. Both parties hope to achieve industrial resonance through party building leadership and contribute to the development of the health industry in the Binhai New Area.

Strength crowned, Chuangyuan Biotechnology won two Science and Technology Awards from the China Food Industry Association.

2024-12-17

On December 16, 2024, the 22nd China Food Safety Conference and the 2024 National Food Industry Science and Technology Progress Conference, themed "Implementing Food Safety Strategy to Support the Construction of a Healthy China," was grandly held in Beijing. During the conference, the award ceremony for the 2024 National Food Industry Science and Technology Progress Conference was also held. Tianjin Chuangyuan Biotechnology Co., Ltd. won the second prize for scientific and technological progress in the "2023 China Food Industry Association Science and Technology Award" for two projects: "Key Technology Breakthrough and Industrial Application of New Postbiotics Segmented Solid-State Fermentation" and "Development and Application of Key Technologies and Equipment for Plant Polysaccharide Efficacy Verification and Extraction."

Chuangyuan Biotech's lactic acid bacteria IOB701 post-fermentation probiotic powder has been granted a national invention patent.

2024-12-13

On December 13, 2024, Tianjin Chuangyuan Biotechnology Co., Ltd. received an invention patent certificate from the National Intellectual Property Administration for its independently developed and filed method and application for the preparation of Lactobacillus plantarum IOB701 fermented postbiotics powder (Patent No.: ZL 202411354886.X). This invention provides a method and application for the preparation of Lactobacillus plantarum IOB701 fermented postbiotics powder, which relates to the field of microbiology. The Lactobacillus plantarum IOB701 was preserved on July 10, 2018, at the General Microbial Culture Collection Center of the China Microbial Strain Preservation Management Committee, abbreviated as CGMCC, with the preservation address at No. 3, Courtyard 1, Beichen West Road, Chaoyang District, Beijing, and the preservation number CGMCC No. 16077. Using grains or legumes treated with low oxygen stress as the fermentation substrate, the Lactobacillus plantarum IOB701 fermentation resulted in postbiotics powder, which, according to animal experiments, has been shown to improve chronic unpredictable mild stress-induced depressive-like behavior in mice.

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