The realization of industrialization of segmented solid-state fermentation technology for multiple probiotics.

In 1993, entered the field of technical research on segmented solid-state fermentation of probiotic core strains.

In 2008, became one of the pioneers in the field of segmented solid-state fermentation technology for probiotics in China.

In 2013, mastered various segmented solid-state fermentation technologies for probiotics, with some research results published in internationally renowned journals.

In 2018, Tianjin Chuangyuan Biotechnology Co., Ltd. was officially established; in the same year, obtained a production license, and the first production line was officially completed and put into operation.

In 2020, the company's 'multiple probiotic segmented solid-state fermentation technology' was recognized as 'international advanced level' scientific and technological achievement.

In 2022, initiated the construction of the second-phase production base and the key laboratory project for probiotics and postbiotics technology and application.

2023年，In 2023, the 16,000 m² factory of the second-phase production base was fully put into operation, with 7 major production units meeting the production needs of mainstream market dosage forms.Approved as the 'Tianjin Key Laboratory of Edible Probiotics', and recognized as a 'specialized, refined, distinctive, and innovative' small and medium-sized enterprise in Tianjin.Selected for the '2023 Tianjin Digital Workshop and Smart Factory' list.

2024年，In 2024, completed the relocation of the headquarters, marking a new era in the company's development, while the original production base.(renamed as Chuangyuan Tianjiu Base) will continue to be retained.Expanded into the special medical purpose food sector, completed the equity restructuring of Tianjin Tianyuan Special Medical Food Co., Ltd. (Chuangyuan Bio holds 70%), and is preparing for on-site verification.Expanded into the health food sector, with the application for production license approval in progress.

As of now, the company has invested over 40 million yuan in research and development, holds 30 invention patents, 24 utility model patents, and has launched over 30 self-owned brand products; has served more than 200 clients, with over 300 ODM/OEM products.

Strong research capabilities

Core product features of probiotics

Strong research capabilities

Core product features of probiotics

2024-12-23

In December 2024, Tianjin Chuangyuan Biotechnology Co., Ltd. and Haihe Dairy jointly held a series of themed activities titled "Party Building Mutual Visits and Learning" to further promote the deep integration of both parties' party building work and business development. During the event, both sides will conduct company visits and on-site discussions. Recently, Haihe Dairy made an initial visit and, after gaining a deep understanding of Chuangyuan Biotech's products, expressed high recognition and close attention, laying a solid foundation for future cooperation. Subsequently, both parties engaged in detailed communication on the core topics of "exchange of party building experiences and sharing of business resources," discussing standardized construction of party branches, distinctive party building measures, and the promotion of party-business integration. They also conducted in-depth exchanges on aspects such as corporate cooperation, product intercommunication, and information sharing, jointly exploring new paths for the development of the health industry under the guidance of party building, providing more possibilities for further establishing a "symbiotic, mutually promoting, and win-win" cooperative relationship. Both parties hope to achieve industrial resonance through party building leadership and contribute to the development of the health industry in the Binhai New Area.

Strength crowned, Chuangyuan Biotechnology won two Science and Technology Awards from the China Food Industry Association.

2024-12-17

On December 16, 2024, the 22nd China Food Safety Conference and the 2024 National Food Industry Science and Technology Progress Conference, themed "Implementing Food Safety Strategy to Support the Construction of a Healthy China," was grandly held in Beijing. During the conference, the award ceremony for the 2024 National Food Industry Science and Technology Progress Conference was also held. Tianjin Chuangyuan Biotechnology Co., Ltd. won the second prize for scientific and technological progress in the "2023 China Food Industry Association Science and Technology Award" for two projects: "Key Technology Breakthrough and Industrial Application of New Postbiotics Segmented Solid-State Fermentation" and "Development and Application of Key Technologies and Equipment for Plant Polysaccharide Efficacy Verification and Extraction."

Chuangyuan Biotech's lactic acid bacteria IOB701 post-fermentation probiotic powder has been granted a national invention patent.

2024-12-13

On December 13, 2024, Tianjin Chuangyuan Biotechnology Co., Ltd. received an invention patent certificate from the National Intellectual Property Administration for its independently developed and filed method and application for the preparation of Lactobacillus plantarum IOB701 fermented postbiotics powder (Patent No.: ZL 202411354886.X). This invention provides a method and application for the preparation of Lactobacillus plantarum IOB701 fermented postbiotics powder, which relates to the field of microbiology. The Lactobacillus plantarum IOB701 was preserved on July 10, 2018, at the General Microbial Culture Collection Center of the China Microbial Strain Preservation Management Committee, abbreviated as CGMCC, with the preservation address at No. 3, Courtyard 1, Beichen West Road, Chaoyang District, Beijing, and the preservation number CGMCC No. 16077. Using grains or legumes treated with low oxygen stress as the fermentation substrate, the Lactobacillus plantarum IOB701 fermentation resulted in postbiotics powder, which, according to animal experiments, has been shown to improve chronic unpredictable mild stress-induced depressive-like behavior in mice.

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