Innovative Breakthroughs, Returning with Honors | Chuangyuan Bio's AAES2024 Natural Health Products Exhibition Successfully Concluded

On October 12, the AAES2024 Natural Health Products Industry Conference and the concurrent AAES2024 Natural Health Products Exhibition (referred to as AAES2024), organized by Zhitaiqiao, successfully concluded at the Nanjing International Exhibition Center (Xinzhuang) after three days. The conference, themed "Technology for the Future," featured five forums and gathered over 120 industry leaders to help companies gain insights into global industry development trends, provide inspiration for product differentiation development, and assist in seizing industry development opportunities. The exhibition area reached 10,000 square meters, attracting over 200 exhibitors and showcasing more than 6,000 innovative raw materials and products from around the world, drawing over 5,000 professional visitors.

As a pioneer and practitioner in the micro-ecological preparations and postbiotics industry, Chuangyuan Bio showcased functional raw materials such as probiotics, postbiotics, and small molecule peptides, as well as product solutions covering various dosage forms.These include powders, liquids, tablets, gel candies, and dairy products; the star ingredient IOBPRO was highlighted on-site.^®Probiotic segmented fermentation solid-state postbiotic powder and the 【Postbiotic】 series of new consumer products aim to provide blue ocean materials for clients in the food and health industries to break through the red ocean market.⁺Innovation Breakthrough:

Sharing of the research topic "The Correlation Study of Lactobacillus paracasei IOB413 Postbiotics and the Gut-X Axis"At the industry conference, Han Xuemei, manager of the Basic Research Department of Chuangyuan Bio's R&D Center, shared the topic "The Correlation Study of Lactobacillus paracasei IOB413 Postbiotics and the Gut-X Axis" with guests and industry peers, providing in-depth analysis from various aspects including the green intelligent manufacturing of postbiotics, production processes, application directions of Lactobacillus paracasei IOB413 postbiotics, relevant functional experimental validations, and its innovative value in health foods and functional foods.

Returning with honors: Double awards well-deserved

At the award ceremony of the 7th "Natural New Forces" Innovation Selection Activity organized by Zhitaiqiao, Chuangyuan Bio's Jiuqing Ganshu

Turmeric Pueraria Compound Oligopeptide Drink won the "Innovative Product · National Trend Innovation Award," and Lactobacillus paracasei IOB413 Fermented Postbiotic Powder won the "Innovative Raw Material · Source Innovation Application Award."^®Jiuqing Ganshu

Turmeric Pueraria Compound Oligopeptide Drink^®Turmeric Pueraria Compound Oligopeptide Drink is a new type of composite micro-ecological preparation that combines probiotics, prebiotics, postbiotics, and natural plant ingredients (such as Pueraria, turmeric, Ziziphus jujuba, and Cirsium setosum). It scientifically combines innovative patented postbiotics (IOB413 postbiotic powder) with traditional food-medicine homologous functional ingredients and has been validated through multiple animal experiments.

Turmeric Pueraria Compound Oligopeptide Drink^®Lactobacillus paracasei IOB413 Fermented Postbiotic PowderThe "Lactobacillus paracasei IOB413 Fermented Postbiotic Powder" project utilizes the self-isolated and screened Lactobacillus paracasei IOB413 strain.Based on the strain characteristics, it simulates a healthy intestinal fermentation environment in vitro,

using patented equipment

andinternationally advanced segmented solid-state fermentation technologyto obtain inactivated bacterial bodies, their lysates, metabolites, and nutritional components of fermentation substrates, demonstrating the advantages of the new postbiotics in "filling gaps" and "addressing shortcomings," solving issues such as poor stability of probiotics, narrow application range, and high fermentation contamination, thus filling the gap in the solid-state fermentation postbiotics industry.This project is based on scientific evidence, validated through results from cell models, animal experiments, and clinical evaluations, providing a full dosage form and covering all populations with nutritional health product solutions, empowering the functional food industry chain upgrade, improving public health through modern technology, and meeting the diverse health needs of the Chinese population through nutritional intervention.和具有国际先进水平的分段固态发酵技术，获得灭活菌体及其裂解物、代谢产物及发酵底物营养成分的后生元，发挥了新型后生元“填空白”和“补短板”的优势，解决了益生菌稳定性差、应用范围窄、发酵污染大等难题，填补了固态发酵益生菌后生元行业空白。

该项目以科学循证为基础，经细胞模型、动物试验、临床评价等体外体内验证结果，以提供全剂型、覆盖全人群的营养健康产品解决方案，赋能功能食品产业链升级，以现代科技改善全民健康，通过营养干预手段满足国人多样化健康需求。

The signing ceremony for the establishment of an off-campus practice base between Chuangyuan Biotechnology and the School of Life Sciences at Tianjin University has been successfully concluded.

Congratulations | Chuangyuan Biotechnology Party Branch has been awarded the titles of 'Advanced Grassroots Party Organization of Binhai New Area, Tianjin' and 'Advanced Grassroots Party Organization of Tianjin Binhai High-tech Zone'.

The signing ceremony for the establishment of an off-campus practice base between Chuangyuan Biotechnology and the School of Life Sciences at Tianjin University has been successfully concluded.

2024-12-23

In December 2024, Tianjin Chuangyuan Biotechnology Co., Ltd. and Haihe Dairy jointly held a series of themed activities titled "Party Building Mutual Visits and Learning" to further promote the deep integration of both parties' party building work and business development. During the event, both sides will conduct company visits and on-site discussions. Recently, Haihe Dairy made an initial visit and, after gaining a deep understanding of Chuangyuan Biotech's products, expressed high recognition and close attention, laying a solid foundation for future cooperation. Subsequently, both parties engaged in detailed communication on the core topics of "exchange of party building experiences and sharing of business resources," discussing standardized construction of party branches, distinctive party building measures, and the promotion of party-business integration. They also conducted in-depth exchanges on aspects such as corporate cooperation, product intercommunication, and information sharing, jointly exploring new paths for the development of the health industry under the guidance of party building, providing more possibilities for further establishing a "symbiotic, mutually promoting, and win-win" cooperative relationship. Both parties hope to achieve industrial resonance through party building leadership and contribute to the development of the health industry in the Binhai New Area.

Strength crowned, Chuangyuan Biotechnology won two Science and Technology Awards from the China Food Industry Association.

2024-12-17

On December 16, 2024, the 22nd China Food Safety Conference and the 2024 National Food Industry Science and Technology Progress Conference, themed "Implementing Food Safety Strategy to Support the Construction of a Healthy China," was grandly held in Beijing. During the conference, the award ceremony for the 2024 National Food Industry Science and Technology Progress Conference was also held. Tianjin Chuangyuan Biotechnology Co., Ltd. won the second prize for scientific and technological progress in the "2023 China Food Industry Association Science and Technology Award" for two projects: "Key Technology Breakthrough and Industrial Application of New Postbiotics Segmented Solid-State Fermentation" and "Development and Application of Key Technologies and Equipment for Plant Polysaccharide Efficacy Verification and Extraction."

Chuangyuan Biotech's lactic acid bacteria IOB701 post-fermentation probiotic powder has been granted a national invention patent.

2024-12-13

On December 13, 2024, Tianjin Chuangyuan Biotechnology Co., Ltd. received an invention patent certificate from the National Intellectual Property Administration for its independently developed and filed method and application for the preparation of Lactobacillus plantarum IOB701 fermented postbiotics powder (Patent No.: ZL 202411354886.X). This invention provides a method and application for the preparation of Lactobacillus plantarum IOB701 fermented postbiotics powder, which relates to the field of microbiology. The Lactobacillus plantarum IOB701 was preserved on July 10, 2018, at the General Microbial Culture Collection Center of the China Microbial Strain Preservation Management Committee, abbreviated as CGMCC, with the preservation address at No. 3, Courtyard 1, Beichen West Road, Chaoyang District, Beijing, and the preservation number CGMCC No. 16077. Using grains or legumes treated with low oxygen stress as the fermentation substrate, the Lactobacillus plantarum IOB701 fermentation resulted in postbiotics powder, which, according to animal experiments, has been shown to improve chronic unpredictable mild stress-induced depressive-like behavior in mice.

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