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2022.07.01

FAQ Heavy Release | Understand 20 Hot Topics about Shengyuan at Once (Part 1)

What exactly are postbiotics? What are the differences between postbiotics, probiotics, and prebiotics? Why can 'dead bacteria' also be effective? What is the current state of development and regulation in the postbiotic industry?

FAQ Heavy Release | Understand 20 Hot Topics about Shengyuan at Once (Part 1)

2022.06.30

Cigarette smoke promotes the occurrence and development of colorectal cancer by regulating the gut microbiota and related metabolites (Part Four)

Experimental results indicate that quitting smoking is one of the practical methods to prevent CRC, at least by rebuilding a healthy gut microbiome.

Cigarette smoke promotes the occurrence and development of colorectal cancer by regulating the gut microbiota and related metabolites (Part Four)

2022.06.24

Cigarette smoke promotes the occurrence and development of colorectal cancer by regulating the gut microbiota and related metabolites (III)

Cigarette smoke enhances the expression of pro-inflammatory signaling genes in the occurrence of intestinal tumors. The changes in the microbiome and metabolome caused by cigarette smoke may impair intestinal barrier function...

Cigarette smoke promotes the occurrence and development of colorectal cancer by regulating the gut microbiota and related metabolites (III)

2022.06.13

Cigarette smoke promotes the occurrence and development of colorectal cancer by regulating the gut microbiota and related metabolites (Part II)

The changes in fecal metabolites after smoke exposure were determined by liquid chromatography, and mass spectrometry (MS)/MS analysis was performed on mouse feces. Orthogonal partial least squares discriminant analysis showed that the fecal metabolite profiles of smoke-exposed mice were significantly different from those of smoke-free mice (Figure 3A). Compared to the smoke-free control mice, 41 metabolites were altered in the feces of cigarette smoke-exposed mice (Figure 3B). The altered metabolites were enriched or depleted in different metabolomic signaling pathways (Figure 3C). Bile acid biosynthesis was the most enriched pathway in cigarette smoke-exposed mice compared to smoke-free mice.

Cigarette smoke promotes the occurrence and development of colorectal cancer by regulating the gut microbiota and related metabolites (Part II)

2022.05.27

Cigarette smoke promotes the occurrence and development of colorectal cancer by regulating the gut microbiota and related metabolites (I)

Colorectal cancer (CRC) is one of the most common cancers worldwide. Although there are many early screening and prevention strategies for colorectal cancer, its burden is expected to increase further. There is evidence supporting the association between lifestyle factors such as diet, smoking, obesity, and exercise with CRC. Smoking increases the risk of lung cancer, with approximately 80% of primary lung cancer attributable to smoking.

Cigarette smoke promotes the occurrence and development of colorectal cancer by regulating the gut microbiota and related metabolites (I)

2022.05.27

Microcapsules for the synergistic delivery of probiotics and postbiotics from microfluidics for the treatment of colitis (Part II)

To explore the protective effect of IPA@MC on colitis in vivo, mice were orally administered IPA@MC, IPA, and MC for 5 consecutive days, and then colitis was induced for 7 days using dextran sulfate sodium (DSS) in their drinking water...

Microcapsules for the synergistic delivery of probiotics and postbiotics from microfluidics for the treatment of colitis (Part II)
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